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Alopecia totalis

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Title: Alopecia totalis  
Author: World Heritage Encyclopedia
Language: English
Subject: Hair loss, Alopecia areata, Management of hair loss, Human hair, Hypertrichosis
Collection: Conditions of the Skin Appendages, Hair Disease, Hair Diseases, Human Hair
Publisher: World Heritage Encyclopedia

Alopecia totalis

Alopecia totalis
A woman with alopecia totalis.
Classification and external resources
ICD-10 L63.0

Alopecia totalis is the loss of all head hair. Its causes are unclear, but believed to be autoimmune. Stress is thought to be a contributor in alopecia areata. However, many with the disorder lead relatively low stress lives.


  • Treatment 1
  • See also 2
  • References 3
  • External links 4


Methotrexate and corticosteroids are proposed treatments.[1]

Scalp cooling has specifically been used to prevent alopecia in docetaxel chemotherapy,[2] although it has been found prophylactic in other regimens as well.[3][4][5] Treatment effects may take time to resolve, with one study showing breast cancer survivors wearing wigs up to 2 years after chemotherapy.[6]

See also


  1. ^ Joly, Pascal (2006). "The use of methtrexate alone or in combination with low doses of oral corticosteroids in the treatment of alopecia totalis or universalis". Journal of the American Academy of Dermatology 55 (4): 632–6.  
  2. ^ Hurk, C. J. G.; Breed, W. P. M.; Nortier, J. W. R. (2012). "Short post-infusion scalp cooling time in the prevention of docetaxel-induced alopecia". Supportive Care in Cancer 20 (12): 3255–3260.  
  3. ^ Lemieux, J. (2012). "Reducing chemotherapy-induced alopecia with scalp cooling". Clinical advances in hematology & oncology : H&O 10 (10): 681–682.  
  4. ^ Van Den Hurk, C. J.; Peerbooms, M.; Van De Poll-Franse, L. V.; Nortier, J. W.; Coebergh, J. W. W.; Breed, W. P. (2012). "Scalp cooling for hair preservation and associated characteristics in 1411 chemotherapy patients - Results of the Dutch Scalp Cooling Registry". Acta Oncologica 51 (4): 497–504.  
  5. ^ Yeager, C. E.; Olsen, E. A. (2011). "Treatment of chemotherapy-induced alopecia". Dermatologic Therapy 24 (4): 432–442.  
  6. ^ Oshima, Y.; Watanabe, T.; Nakagawa, S.; Endo, A.; Shiga, C. (2012). "A questionnaire survey about hair loss after chemotherapy for breast cancer". Gan to kagaku ryoho. Cancer & chemotherapy 39 (9): 1375–1378.  

External links

  • Children's Alopecia Project
  • Alopecia World
  • Alopecia Online, UK
  • Alopecia Totalis and Universalis Support Community
  • Alopecia Totalis and Universalis Case Study
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