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Anti-p62 antibodies

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Title: Anti-p62 antibodies  
Author: World Heritage Encyclopedia
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Subject: Autoantibody, Autoimmune disease
Publisher: World Heritage Encyclopedia

Anti-p62 antibodies

Nucleoporin 62kDA
Autoantigen gene NUP62
Affected organ(s) Bile duct
Primary biliary cirrhosis
HLA associations DR2 (weak)

Anti-p62 antibodies (AP62A) are found in a primary biliary cirrhosis.[1] p62 is also more frequent in Stage IV primary biliary cirrhosis and is prognostic for severe disease.[2][3] The autoantigen is the nucleoporin 62kDA protein.


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