World Library  
Flag as Inappropriate
Email this Article

Gerald M. Rubin

Article Id: WHEBN0014483749
Reproduction Date:

Title: Gerald M. Rubin  
Author: World Heritage Encyclopedia
Language: English
Subject: Janelia Research Campus, Transposable element, Christopher Chang, Jerard Hurwitz, Christopher T. Walsh
Collection:
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Gerald M. Rubin

Gerald Rubin
Born Gerald Mayer Rubin
1950 (age 64–65)
Fields
Institutions
Alma mater
Thesis Studies on 5.8S ribosomal RNA (1974)
Notable awards
Website
/gerald-m-rubin/scientists.org.hhmiwww

Gerald Mayer Rubin (born 1950) is an American biologist, notable for pioneering the use of transposable P elements in genetics, and for leading the public project to sequence the Drosophila melanogaster genome. Related to his genomics work, Rubin's lab is notable for development of genomics tools and whole-genome studies of gene regulation. Rubin also serves as Vice President of the Howard Hughes Medical Institute and Executive Director of the Janelia Farm Research Campus.[2][3][4][5]

Biography

Rubin was born in Boston, Massachusetts, in 1950, attending the Boston Latin School. Rubin completed his undergraduate degree in biology at MIT, working at Cold Spring Harbor Laboratory during the summer.[6][7] He completed his Ph.D. at the University of Cambridge,[8] funded by the MRC in 1974,[9] for studies on 5.8S ribosomal RNA.

Career

Following his PhD, Rubin did postdoctoral research at Stanford University with David Hogness.[10]

Rubin's first faculty position was at Harvard Medical School, followed by the Carnegie Institution of Washington; in 1983 he accepted a faculty appointment at the University of California, Berkeley. He was appointed a Howard Hughes Medical Investigator in 1987. He is currently the MacArthur Professor of Genetics, Genomics and Development, in Berkeley's Department of Molecular and Cell Biology.

Rubin has taken a leading role in a number of high-profile scientific research projects.[11][12][13][14][15][16][17][18][19][20][21] As the director of the Berkeley Drosophila Genome Project, he led the public effort to sequence Drosophila melanogaster.[22] As Vice President of the Howard Hughes Medical Institute, Rubin led the development of HHMI's Janelia Farm Research Campus, an independent biomedical research institute in Virginia.[6][7]

His lab is particularly known for its development of genomics tools, studies of gene regulation, and other genome-wide research.

Awards and honours

Rubin has won numerous awards including:

References

  1. ^ a b Orr-Weaver, T. (2003). "The 2003 George W. Beadle Medal; Gerald M. Rubin and Allan C. Spradling". Genetics 164 (4): 1248–1249.  
  2. ^ Gerald M. Rubin from the Scopus bibliographic database.
  3. ^ Rubin, G. M. (2006). "Janelia Farm: An Experiment in Scientific Culture". Cell 125 (2): 209–212.  
  4. ^ Rubin faculty profile
  5. ^ http://www.sciencewatch.com/sept-oct99/sw_sept-oct99_page3.htm HMI's Gerald M. Rubin: The Benefits of Genomics, ScienceWatch, v.10, n.5 (Sept./Oct. 1999)
  6. ^ a b UPI, "Gerald Rubin: Science Far Too Conservative", April 20, 2006 (discussing Janelia Farm).
  7. ^ a b Tim Studt, "Architect of the Future: Refocusing on Basic Research", R&D Magazine.
  8. ^ Rubin, Gerald Mayer (1974). Studies on 5.8 S Ribo-somal RNA (PhD thesis). University of Cambridge. 
  9. ^ Rubin, G. (1974). "Three forms of the 5.8-S ribosomal RNA species in Saccharomyces cerevisiae". European journal of biochemistry / FEBS 41 (1): 197–202.  
  10. ^ Rubin, G.; Hogness, D. (1975). "Effect of heat shock on the synthesis of low molecular weight RNAs in drosophilia: Accumulation of a novel form of 5S RNA". Cell 6 (2): 207–213.  
  11. ^ Mammalian Gene Collection Program Team; Strausberg, R. L.; Feingold, E. A.; Grouse, L. H. et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences".  
  12. ^ Xu, T; Rubin, G. M. (1993). "Analysis of genetic mosaics in developing and adult Drosophila tissues". Development (Cambridge, England) 117 (4): 1223–37.  
  13. ^ Harris, M. A.; Clark, J; Ireland, A; Lomax, J; Ashburner, M; Foulger, R; Eilbeck, K; Lewis, S; Marshall, B; Mungall, C; Richter, J; Rubin, G. M.; Blake, J. A.; Bult, C; Dolan, M; Drabkin, H; Eppig, J. T.; Hill, D. P.; Ni, L; Ringwald, M; Balakrishnan, R; Cherry, J. M.; Christie, K. R.; Costanzo, M. C.; Dwight, S. S.; Engel, S; Fisk, D. G.; Hirschman, J. E.; Hong, E. L. et al. (2004). "The Gene Ontology (GO) database and informatics resource". Nucleic Acids Research 32 (Database issue): D258–61.  
  14. ^ Spradling, A.; Rubin, G. (1982). "Transposition of cloned P elements into Drosophila germ line chromosomes". Science 218 (4570): 341–347.  
  15. ^ Rubin, G.; Spradling, A. (1982). "Genetic transformation of Drosophila with transposable element vectors". Science 218 (4570): 348–353.  
  16. ^ Miklos, G.; Rubin, G. (1996). "The role of the genome project in determining gene function: Insights from model organisms". Cell 86 (4): 521–529.  
  17. ^ Adams, M.; Celniker, S.; Holt, R.; Evans, C.; Gocayne, J.; Amanatides, P.; Scherer, S.; Li, P.; Hoskins, R.; Galle, R. F.; George, R. A.; Lewis, S. E.; Richards, S.; Ashburner, M.; Henderson, S. N.; Sutton, G. G.; Wortman, J. R.; Yandell, M. D.; Zhang, Q.; Chen, L. X.; Brandon, R. C.; Rogers, Y. H.; Blazej, R. G.; Champe, M.; Pfeiffer, B. D.; Wan, K. H.; Doyle, C.; Baxter, E. G.; Helt, G.; Nelson, C. R. (2000). "The genome sequence of Drosophila melanogaster". Science 287 (5461): 2185–2195.  
  18. ^ Rubin, G.; Yandell, M.; Wortman, J.; Gabor Miklos, G.; Nelson, C.; Hariharan, I.; Fortini, M.; Li, P.; Apweiler, R.; Fleischmann, W.; Cherry, J. M.; Henikoff, S.; Skupski, M. P.; Misra, S.;  
  19. ^  
  20. ^ Rubin, G. M. (2001). "The draft sequences: Comparing species". Nature 409 (6822): 820–821.  
  21. ^ Spellman, P. T.; Rubin, G. M. (2002). "Evidence for large domains of similarly expressed genes in the Drosophila genome". Journal of Biology 1 (1): 5.  
  22. ^ Adams, M.; Celniker, S.; Holt, R.; Evans, C.; Gocayne, J.; Amanatides, P.; Scherer, S.; Li, P.; Hoskins, R.; Galle, R. F.; George, R. A.; Lewis, S. E.; Richards, S.; Ashburner, M.; Henderson, S. N.; Sutton, G. G.; Wortman, J. R.; Yandell, M. D.; Zhang, Q.; Chen, L. X.; Brandon, R. C.; Rogers, Y. H.; Blazej, R. G.; Champe, M.; Pfeiffer, B. D.; Wan, K. H.; Doyle, C.; Baxter, E. G.; Helt, G.; Nelson, C. R. (2000). "The genome sequence of Drosophila melanogaster". Science 287 (5461): 2185–2195.  
  23. ^ Robert Sanders, "UC Berkeley's Gerald Rubin shares AAAS prize with Celera's Craig Venter for sequencing genome of the fruit fly", UC Berkeley Campus News, Feb. 20, 2001.


This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 



Copyright © World Library Foundation. All rights reserved. eBooks from World eBook Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.