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Granulomatous perioral dermatitis

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Title: Granulomatous perioral dermatitis  
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Language: English
Subject: Perioral dermatitis, Periorbital dermatitis
Publisher: World Heritage Encyclopedia

Granulomatous perioral dermatitis

Perioral dermatitis
Classification and external resources
10 9 DiseasesDB MedlinePlus eMedicine MeSH D019557

Perioral dermatitis (also called periorifical dermatitis), is skin disease characterised by multiple small (1 - 2 mm) papules, pustules and vesicles which are localised to the perioral skin (around the mouth), nasolabial folds (around the nostrils), or perioccular area (around the eyes). It most commonly affects women between the ages of 20 and 45 years, but may also affect children, men and the elderly. It is not uncommon, and has a tendency to recur in individuals who have had it once.

Symptoms and signs

Perioral dermatitis may be asymptomatic, or may be associated with a burning, stinging sensation in the affected areas.

When periorbital dermatitis is found in otherwise healthy prepubertal children, with a profusion of grouped papules on the perioral, periocular, and perinasal areas, the condition is referred to as Granulomatous perioral dermatitis.[1]


A diagnosis of perioral dermatitis is typically made based on the characteristics of the rash. A skin biopsy is usually not required to make the diagnosis, but can be helpful to rule out other skin diseases which may resemble perioral dermatitis.

Other skin diseases which may resemble perioral dermatitis include:

  • Rosacea
  • Acne vulgaris
  • Seborrheic dermatitis
  • Allergic contact dermatitis
  • Irritant contact dermatitis


Perioral dermatitis is a self-limited condition which will typically resolve within a few months without pharmacological therapy. However, many patients request treatment for cosmetic reasons. Topical corticosteroids should be ceased entirely when possible, or a less potent formulation used in order to slowly reduce dependency. Pharmacological therapy is usually with tetracycline antibiotics or erythromycin in children and pregnant women.[2]

See also


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