Nucleoporins

Nucleoporin
File:PDB 3cqg EBI.jpg
Structure of nucleoporin Nup107/Nup133 interaction complex, delta finger mutant.
Identifiers
Symbol Nucleoporin
Pfam InterPro IPR004870

The nucleoporins are a family of proteins which are the constituent building blocks of the nuclear pore complex.[1] The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the cell nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. Nuclear pores in turn allow the transport of water-soluble molecules across the nuclear envelope.

The proteins involved are named for their molecular weight (in kilo Daltons), and include the following:

References

External links

  • Medical Subject Headings (MeSH)
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